Nuclear medicine is an increasingly important dicipline in modern healthcare, applied to treat and diagnose a broad spectrum of diseases, including those related to cancer, the cardiovascular system and the brain. Radiopharmaceuticals, or radioisotopes, are used by highly specialized hospital units, serving many patients, and at the same time contributing to critical research and development.
In nuclear medicine a pharmaceutical compounds is combined with a radionuclide to form radiopharmaceuticals. Technetium-99m (Tc-99m) is a radionuclide which often is used, as it has many useful properties as a gamma-emitting tracer nuclide.
Radiopharmaceuticals are used as tracers in the diagnosis and treatment of many diseases, as they can localize specific organs or cellular receptors. This property allows nuclear medicine the ability to image the extent of a disease process in the body at an earlier stage than other diagnostic tests. In a sense, is radiology done inside out because it records radiation emitting from within the body, rather than radiation that is generated by external sources like x-rays.
Radiopharmaceutical cold kit is the API that do not contain radioactivity. Cold kits have been developed to produce quality radiopharmaceuticals at the site of use when mixed with the requisite amount of a radioisotope.
Tracer Pharma API products are all used in cold kits.
Equipment & software
Nuclear medicines allow the ability to image the extent of a disease process in the body by using advanced cameras (SPECT, PET, CT) in two- and three-dimensional images in combination with advanced reconstruction algorithms and other software developments.
SPECT imaging is performed by using a gamma camera to acquire multiple 2-D images projections, from multiple angles. A computer is then used to apply a tomographic reconstruction algorithm to the multiple projections, yielding a 3-D dataset. This dataset may then be manipulated to show thin slices along any chosen axis of the body.
PET is a nuclear medical imaging technique that produces a three-dimensional image or picture of functional processes in the body. PET scans are increasingly read alongside CT or magnetic resonance imaging (MRI) scans, with the combination (called co-registration) giving both anatomic and metabolic information (i.e., what the structure is, and what it is doing biochemically). Because PET imaging is most useful in combination with anatomical imaging, such as CT, modern PET scanners are now available with integrated high-end multi-detector-row CT scanners (so-called “PET/CT”). Because the two scans can be performed in immediate sequence during the same session, with the patient not changing position between the two types of scans, the two sets of images are more-precisely registered, so that areas of abnormality on the PET imaging can be more perfectly correlated with anatomy on the CT images.